The two ways of every gesture
Drag, or click and click

A rectangle dragged while holding SHIFT: the constraint keeps it square

Drag or click

Every drawing tool places points: two for a box or a line, three for an arc or a linear dimension. You place the points in two ways:

  1. by dragging from one point to the next;
  2. with a click, then another click where the next point goes.

The second way really matters: between the two clicks you can turn the wheel and pan the view, and it is the only way to snap to a point that was off screen at the start. Points are in drawing coordinates, so zoom and pan do not distort the shape you are making.

Selection handles also accept both ways: once you pick up a handle with a click, the gesture continues until you click again.

The exceptions are the free rotate and scale tools (A and S): they work only by dragging.

Click or drag

For a gesture to become a drag you must move a few pixels: 10 on handles and on path points, 4 from empty space (the selection marquee) and for the Pen tool's direction handles. Below that distance the gesture counts as a click.

SHIFT, a single constraint

Holding ⇧ constrains the gesture, and it works even if you press it after the gesture has started (from the next movement). What it means is up to the tool:

GestureWith SHIFT
Draw a line, a pathangles at 45° from the first point
Rectangle, ellipse, pagesquare, circle
Scaleproportionally
Rotatein increments of Rotation step (15° by default)
Moveonly horizontally or vertically, and without snapping

With the constraint on, from the second point the drawing does not snap.

ALT

⌥ changes the gesture in ways that depend on the tool: it grows rectangles and ellipses from the center, duplicates while moving or rotating, scales from the center, and on path points removes or adds. The full list is on the Shortcuts page.